Biolife, Volume 3, Issue 2, 2015
DOI: http://dx.doi.org/10.17812/blj2015.32.23

Research Article:



Asmaa Ali Ramadan1,Ahmed Gaber Marie2, Ahmed Hafez Farhoud3, Eman Tayae Elsayed4

1,2 Emergency Department Faculty of Medicine University of Alexandria , Egypt
3Neurosurgery Department Faculty of Medicine University of Alexandria , Egypt 
4Clinical and Chemical  pathology Department , University of Alexandria , Egypt

*Email: asmaaramadan421@gmail.com

Abstract

The purpose of this study is to evaluate the association of coagulopathy and isolated traumatic brain injury as regard its frequency and outcome for patients who developed coagulopathy. This prospective study was conducted to include sixty patients with isolated traumatic brain injury admitted to attending the Emergency Department of Alexandria main university hospital. Primary survey and secondary survey done for those patients, radiological investigations done including CT brain and other radiological investigations to exclude other sources of coagulopathy. This also includes laboratory tests to asses coagulation as INR, platelet count, PTT and FDP for those who showed abnormality with the previous three tests. The frequency of coagulopathy in patients with isolated TBI is 8.3%. Brain edema is the most common CT finding in patients with coagulopathy following TBI as it is present in (80%) of case .SDH is the second most common CT finding in those who develop coagulopathy occurring in (60%) of patients. . All patients with coagulopathy had FDP >10 mic/ml and INR>1.3 ,while PTT >34 seconds in (80%) of patients who develop coagulopathy while platelets <100,000 cell/mm3present in (40%) of patients who developed coagulopathy  .80%of cases who developed coagulopathy had deterioration of GCS, while (40%) developed DIC .Also (80%) had progressive hemorrhagic lesion. . Not all cases of TBI that has high levels of FDP had disseminated intra vascular coagulopathy.

Key words: isolated traumatic brain injury, coagulopathy disseminated intravascular coagulopathy



Published online 28th May, 2015
© 2015 Published by Global Science Publishing Group, USA


How to Cite this Article:

Asmaa Ali Ramadan,Ahmed Gaber Marie, Ahmed Hafez Farhoud, Eman Tayae Elsayed (2015). Prospective study of the association of coagulopathy and isolated traumatic brain injury. Biolife, 3(2), pp 514-518. doi:10.17812/blj2015.32.23

Link to this article: http://biolifejournal.com/10.17812_blj2015.32.23.html
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Prospective study of the association of coagulopathy and isolated traumatic brain injury
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