Biolife, Volume 3, Issue 3, 2015
Significance of Chronic Synthetic Pyrethroid Fenvalerate Administration on
Carbohydrate metabolism in the Muscle, Brain and Intestine of Rana tigrina (Indian
Subbareddy SV1*, Sivasankar R2, Udaykiran V3, Jayantha Rao K4
1 Department of Zoology Loyola Degree College, Pulivendula. A.P.
2-4 Department of Zoology, S.V. University., Tirupati. A.P
The natural pyrethroids are not so much effective against agricultural pests, thus artificial synthesis of synthetic pyrethroids like
fenvalerate was carried out by scientists. Fenvalerate is a insecticide has been proved to be highly toxic to non-target species like
amphibians. In our study, Healthy frogs, Rana tigrina weighing 50 ± 3 gms were collected from the pond, acclimated to the laboratory
conditions in large glass aquaria with water. The frogs were divided into groups of ten animals. They were exposed to different
pesticide concentrations of fenvalerate, both commercial and technical grade, according to biomass ratio as suggested by Doundroff et
al., (1951). The Total carbohydrate content in the present study Control Muscle tissue has shown higher amount of carbohydrates than
compare with Brain and Intestine tissue. Under fenvalerate intoxication, the frog tissues showed consistent decrement in all the
periods and it may be due to rapid utilization to withstand pesticide of stress. Total protein contents in control frog tissues the Muscle
showed higher concentration of proteins than Intestine and Brain. The protein content in experimental frog tissues showed depleted
levels when compared to controls. The significant decrease in protein and it may be due rapid utilization to withstand pesticide of
stress. Total free amino acid (FAA) showed enhanced Intestine FAA levels, the levels in fenvalerate exposed frog tissues were increased
significantly when compared to control. These elevated levels may be due to improved protease activity or enhanced transamination.
From the above observations fenvalerate seems to be hazards to the aquatic life, causing severe biochemical changes and permanent
architectural changes investigated in the present investigation.
Key words: Fenvalerate, Total Carbohydrate content, Total Protein content, Total free amino acid (FAA) levels, Brain, Intestine and
Muscle, Rana Tigrina (Indian Bull Frog).
Published online 24 July, 2015
© 2015 Published by Global Science Publishing Group, USA
How to Cite this Article:
Subbareddy SV, Sivasankar R, Udaykiran V, Jayantha Rao K (2015). Significance of Chronic Synthetic Pyrethroid Fenvalerate
Administration on Carbohydrate metabolism in the Muscle, Brain and Intestine of Rana tigrina (Indian Bull frog). Biolife, 3(3), pp 665-